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Will breath ketones increase when blood ketones are metabolized?

Posted by Michel Lundell on

The transformation of blood ketones (beta-hydroxybutyrate) to acetoacetate (and vice-versa) is not done in your liver. So the cell that need energy will process it there and then, no acetone is produced at this time. Acetone is only produced when fatty acids are metabolized into acetoacetate (or when acetoacetate breaks down, its an unstable molecule).

(image is just an ai image to illustrate fat metabolized into acetoacetate and acetone)
If using exogenous ketones (beta-hydroxybutyrate), the concentration of beta-hydroxybutyrate will increase in blood, as this is a feedback signal to the liver to decrease production of ketone energy, breath ketones will decrease.

Ketones is not a fuel to metabolize fat, it is a product of metabolize fat. Blood ketones are also a signal to stop metabolize fat. Breath ketones is a product of the process of metabolize the fat into ketones (AcetoAcetate).

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